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UNIV - Research Specialist III - Surgery: General Surgery Research

Apply now Job no: 520916
Entity: MUSC University
Department: COLLEGE OF MEDICINE - COM-Surgery
Sub Department: UNIV-2270300-General Surgery
Work type: Full-Time
Employee Type: UNIV - Research Grant
Location: Charleston, SC-Main Campus
Categories: RESEARCH
Pay scale: UNIV-Band 6: $40,759.00 - $58,086.00 - $75,413.00 (min - mid - max)

Job Duties:
15Responsible for the maintenance of equipment in the lab. Manage and assist the surgeries, diagnostic analysis and other procedures with small animals. Manage the lab meetings, manuscript preparations as deemed appropriate by the PI.Essential
20Manage the process and perform cell and organ culture for in vitro developmental models, including growth and purification of adenoviral and retroviral stocks for in vitro transduction experiments.Essential
20Management: will maintain laboratory equipment, databases and supplies including embryo and histology specimens, assist in orientation and training of new lab personnel including students, postdocs.Essential
20Will have the responsibility for mouse husbandry, colony management and genotyping including sample collection and preparation and PCR genotyping analysis.Essential
25Recombinant molecular work: assist PI, students and postdocs in bacterial recombinant DNA work including cloning of reporter and expression vectors plasmid constructs, PCR and qPCR assay, western blot and protein analysis. Responsible for managing accurate and timely records of all activities, including experimental data, image analysis, etc.Essential


Job Summary: The Department of Surgery is recruiting for a Research Specialist III.

The position will manage the lab which includes laboratory focused on basic mechanisms of congenital heart disease and of hypertension in pregnancy, including work in stem and progenitor cell biology, cardiovascular physiology, mouse models and expression analysis of human placental tissue and related cell lines. Under supervision of PI will hold primary responsibility for the maintenance and logistical organization of a basic science laboratory, with particular emphasis on transgenic mouse colony maintenance, mouse embryonic and adult histology and basic cell, protein recombinant DNA work and small animal physiology studies including small molecule studies. Applicant will have significant responsibilities as the laboratory also training and supervision of a number of undergraduate students and junior technicians.

FLSA: Salaried

Job Duties: 

  • 25% - Recombinant molecular work: assist PI, students and postdocs in bacterial recombinant DNA work including cloning of reporter and expression vectors plasmid constructs, PCR and qPCR assay, western blot and protein analysis. Responsible for managing accurate and timely records of all activities, including experimental data, image analysis, etc. - (Essential)
  • 20% - Will have the responsibility for mouse husbandry, colony management and genotyping including sample collection and preparation and PCR genotyping analysis. - (Essential)
  • 20% - Management: will maintain laboratory equipment, databases and supplies including embryo and histology specimens, assist in orientation and training of new lab personnel including students, postdocs. - (Essential)
  • 20% - Manage the rocess and perform cell and organ culture for in vitro developmental models, including growth and purification of adenoviral and retroviral stocks for in vitro transduction experiments. - (Essential)
  • 15% - Responsible for the maintenance of equipment in the lab. Manage and assist the surgeries, diagnostic analysis and other procedures with small animals. Manage the lab meetings, manuscript preparations as deemed appropriate by the PI. - (Essential)

Minimum Experience and Training Requirements: A bachelor's degree in chemistry, biology, or other natural, life or health care science directly related to the assigned area of research and two years advanced journey-level work experience in a clinical or research setting.

Preferred Experience & Additional Skills: A bachelor’s degree in chemistry, biology, or other natural, life or health care science directly related to the assigned area of research and two years advanced journey-level work experience in a clinical or research setting.

Bachelor’s degree in Biology, Chemistry, Molecular Biology or other life science. Strong organizational, record keeping, interpersonal and communication skills required. Must be able to perform complex calculations, to follow complicated experimental procedures and methods and develop independence with tasks and experimental design and execution. Preference will be given to candidates with knowledge and multiple years experience with laboratory techniques including strong experience with mouse husbandry and colony management, genotyping, PCR and recombinant DNA work, RNA analysis, protein and enzyme assay, and small molecule screening. Prior experience in lab management roles is required. Some weekend and evenings may be required from time to time. Must be able to work with animals.

Payscale Salary Range: UNIV-Band 6: $40,759.00 - $58,086.00 - $75,413.00 (min - mid - max)

Physical Requirements: Ability to perform job functions in an upright position. (Frequent) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb, using step stool. (Infrequent) Ability to work in temperature extremes (32? F to 100? F) when required due to assignments in cold rooms and/or foreign countries. (Infrequent) Ability to work in confined/cramped spaces. (Continuous) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Frequent) Ability to fully use both legs. (Frequent) Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions. (Frequent) Ability to maintain good olfactory sensory function/distinction. (Continuous) Ability to lift materials up to 20 lbs., unassisted. (Infrequent) Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted. (Frequent) Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted. (Infrequent) Ability to lift file boxes, from floor level to counter tops, unassisted. (Frequent) Ability to push/ Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted. (Infrequent) Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted. (Infrequent) Ability to push/pull file boxes from one location to another at floor level. (Frequent) Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted. (Frequent) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to maintain 20/20 vision, corrected. (Continuous) Ability to match or discriminate between colors, normally. (Continuous) Ability to hear and recognize various alarms emitting from work area systems. (Continuous) Ability to hear and/or understand conversations. (Continuous) Ability to work in a darkroom for processing film, etc. (Continuous) Ability to be qualified physically for respirator use, initially and annually. (Continuous)

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.


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Applications close: Eastern Daylight Time

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The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.