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Research Fellow in Drug Discovery Biology

Job No.: 591828

Location: Parkville campus

Employment Type: Full-time

Duration: 12 month fixed-term appointment 

Remuneration: $68,040 - $92,343 pa Level A (plus 9.5% employer superannuation)

  • Be inspired, every day
  • Drive your own learning at one of the world’s top 80 universities
  • Take your career in exciting, rewarding directions

Everyone needs a platform to launch a satisfying career. At Monash, we give you the space and support to take your career in all kinds of exciting new directions. You’ll have access to quality research, infrastructure and learning facilities, opportunities to collaborate internationally, as well as the grants you’ll need to publish your work. We’re a university full of energetic and enthusiastic minds, driven to challenge what’s expected, expand what we know, and learn from other inspiring, empowering thinkers.

The Opportunity

Join one of the world’s leading research groups applying structural biology approaches to tackle key questions on the function of G protein-coupled receptors (GPCRs), the largest family of membrane drug targets. Be part of the innovative research using cryo-electron microscopy to understand the interaction of natural ligands and drugs with their GPCR targets, and how these interactions control signalling.

In your role, you will develop and apply novel methods for formation of stable membrane protein complexes for cryo-EM imaging, along with biochemical and pharmacological characterisation of the proteins and their ligands. Work within a broader team to derive structural information on these proteins, including analysis of imaging data to reconstruct 3D density maps and atomic resolution models.

We are looking for an individual who will have a PhD in an appropriate discipline and extensive experience in membrane protein expression and purification, as well as a high level an understanding of different structural biology approaches for deriving high-resolution protein structure. The successful candidate will also have demonstrated experience in pharmacological and biochemical assessment of proteins. Ideally, this experience will be with GPCRs. You will be able to work both independently and seamlessly within a larger team environment, including highly developed technical skills, and rapid ability to learn new techniques.

This role is a full-time position; however, flexible working arrangements may be negotiated.

At Monash University, we are committed to being a Child Safe organisation. Some positions at the University will require the incumbent to hold a valid Working with Children Check.

Your application must address the selection criteria. Please refer to "How to apply for Monash Jobs".


Professor Patrick Sexton, Lab Head for Drug Discovery Biology Theme, +61 3 9903 9069.

Position Description

Download File Research Fellow in Drug Discovery Biology

Closing Date

Friday 24 May 2019, 11:55 pm AEST

Supporting a diverse workforce

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