The Sahoo Lab is seeking a motivated Postdoctoral Associate to study the genetic and functional mechanisms driving inherited bone marrow failure and predisposition to MDS/AML. This NIH-funded position focuses on defining how germline gain-of-function mutations activate chronic inflammatory signaling, impair hematopoietic stem cell function, and drive progression to myeloid malignancy. The project integrates mouse and iPSC models, CRISPR genome editing, molecular biology, flow cytometry, and single-cell multi-omics to dissect disease mechanisms.

We are committed to mentoring the whole scientist. The successful candidate will lead this project while growing toward research independence, supported by an individualized development plan, structured mentorship, and clear milestones tailored to their career goals. Postdocs are actively mentored to publish, present, build collaborations, and compete for fellowships and career-development awards (e.g., NIH F32, K99/R00). The position is funded for up to three years, with full access to Virginia Tech and Children's National Hospital core facilities and seminars. The candidate will also have the opportunity to mentor and train junior scientists, developing the leadership and mentoring skills essential to an independent career. This is an exciting opportunity to play a foundational role in a growing lab at the Research and Innovation Campus in Washington, DC.

We are building an inclusive, collaborative lab culture and welcome applicants of all backgrounds, identities, and career paths. We are especially eager to hear from individuals historically underrepresented in biomedical research.

• Ph.D. in hematology, genetics, molecular biology, cancer biology, or a related biological science. The Ph.D. must have been awarded no more than four years prior to the effective date of the appointment, with at least one year of eligibility remaining.
• Hands-on experience with mouse models of hematopoiesis and/or cancer, including in vivo techniques such as blood collection and tail vein injection
• Experience with primary hematopoietic stem and progenitor cells and/or iPSC models
• Proficiency in wet-lab techniques, including molecular biology, mammalian cell culture, and flow cytometry
• Experience with CRISPR-based genome editing
• Self-motivated, creative, and detail-oriented
• Excellent organizational and time-management skills
• Excellent communication skills
• Ability to work both independently and as part of a collaborative team
• Experience mentoring or training students and/or research staff

• Familiarity with single-cell multi-omics approaches
• Analysis of large-scale genomic and/or transcriptomic datasets
• Experience with mitochondrial or innate immune/inflammation assays

Exempt: Not eligible for overtime

Restricted

$65,000-$71,000, commensurate with experience

40+

7/24/26

The successful candidate will be required to have a criminal conviction check.

About Virginia Tech

Dedicated to its motto, Ut Prosim (That I May Serve), Virginia Tech pushes the boundaries of knowledge by taking a hands-on, transdisciplinary approach to preparing scholars to be leaders and problem-solvers. A comprehensive land-grant institution that enhances the quality of life in Virginia and throughout the world, Virginia Tech is an inclusive community dedicated to knowledge, discovery, and creativity. The university offers more than 280 majors to a diverse enrollment of more than 36,000 undergraduate, graduate, and professional students in eight undergraduate colleges, a school of medicine, a veterinary medicine college, Graduate School, and Honors College. The university has a significant presence across Virginia, including Blacksburg, the greater Washington, D.C. area, the Health Sciences and Technology Campus in Roanoke, sites in Newport News and Richmond, and numerous Extension offices and research institutes. A leading global research institution, Virginia Tech conducts more than $650 million in research annually.

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